Nerves in cancer.

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The contribution of nerves to the pathogenesis of malignancies has emerged as
an important component of the tumour microenvironment. Recent studies have shown that
peripheral nerves (sympathetic, parasympathetic and sensory) interact with tumour and
stromal cells to promote the initiation and progression of a variety of solid and haematological
malignancies. Furthermore, new evidence suggests that cancers may reactivate nerve-dependent
developmental and regenerative processes to promote their growth and survival. Here we review
emerging concepts and discuss the therapeutic implications of manipulating nerves and neural
signalling for the prevention and treatment of cancer.

Further reading can be found on the link below:

https://mega.nz/#F!sHphVToS!OKqdqBilHR-O7Hcg60J6ng

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